⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466500 | 0.86 | — | — | |
| SCHEMBL1640968 | 0.84 | — | — | |
| SCHEMBL241718 | 0.74 | — | — | |
| SCHEMBL1641262 | 0.74 | HSD17B10 (0.31) | — | |
| SCHEMBL1640279 | 0.73 | CBFB (0.34) | — | |
| SCHEMBL8854499 | 0.73 | — | — | |
| SCHEMBL23628544 | 0.73 | — | — | |
| SCHEMBL1438735 | 0.73 | — | — | |
| SCHEMBL3241102 | 0.72 | CBFB (0.34) | — | |
| SCHEMBL8466468 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140045809-A1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2014-02-13 | — | — | US | disclosed |
| EP-2244701-B1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | TECHNION RES & DEV FOUNDATION (IL) | 2012-05-09 | — | — | EP | disclosed |
| US-20110098262-A1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | TECHNION RESEARCH AND DEVELOPEMENT FOUNDATION, LTD. (IL) | 2011-04-28 | — | — | US | disclosed |
| EP-2244701-A2 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | Technion Research and Development Foundation, Ltd. (IL) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009095923-A2 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD (IL) | 2009-08-06 | — | — | WO | disclosed |