Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CCR4 | P51679 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414139 | 0.90 | KMT2A (0.48) | LMNAJAK1JAK3KMT2AMEN1 | |
| SCHEMBL1640026 | 0.82 | KMT2A (0.54) | LMNAKMT2AMEN1MAOBPGR | |
| SCHEMBL14339623 | 0.79 | LMNA (0.55) | LMNAJAK1JAK3KMT2AMEN1 | |
| SCHEMBL6002524 | 0.79 | KMT2A (0.47) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL14566624 | 0.79 | LMNA (0.53) | LMNAJAK1JAK3KMT2AMEN1 | |
| SCHEMBL6413245 | 0.76 | ALDH1A1 (0.58) | LMNAKMT2AHTTBRD4TP53 | |
| SCHEMBL3066593 | 0.75 | LMNA (0.57) | LMNAKMT2AMEN1MAOBPGR | |
| SCHEMBL23357556 | 0.75 | BCL6 (0.54) | LMNAJAK1JAK3KMT2AMEN1 | |
| SCHEMBL31211542 | 0.75 | BCL6 (0.54) | LMNAJAK1JAK3KMT2AMEN1 | |
| SCHEMBL20773120 | 0.74 | LMNA (0.49) | LMNAJAK1JAK3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098466-A1 | Synthesis Of Triphenodioxazine Pigments | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-04-28 | — | — | US | disclosed |
| WO-2009027014-A2 | SYNTHESIS OF TRIPHENODIOXAZINE PIGMENTS | CLARIANT INTERNATIONAL LTD (CH) | 2009-03-05 | — | — | WO | disclosed |
| EP-2031026-A1 | Synthesis of triphenodioxazine pigments | CLARIANT INTERNATIONAL LTD. (CH) | 2009-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098466-A1 | Synthesis Of Triphenodioxazine Pigments | TYR, SCO2, NDUFS5 | LMNA 4313/4885JAK1 965/4885JAK3 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.