SCHEMBL163947

SCHEMBL163947

C#CC(F)(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25244553 0.82
SCHEMBL2864416 0.77
SCHEMBL5188413 0.74 LMNA (0.33)
SCHEMBL672488 0.72 LMNA (0.38)
SCHEMBL31135124 0.72 LMNA (0.38)
SCHEMBL10826755 0.72 LMNA (0.38)
SCHEMBL6358197 0.72 LMNA (0.38)
SCHEMBL10826142 0.72
SCHEMBL10826125 0.72
SCHEMBL10826113 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024207638-A1 METHOD FOR PREPARING HYDROFLUOROCARBONS AND METHOD FOR PREPARING FLUORINE-CONTAINING ALKYNES 泉州宇极新材料科技有限公司 2024-10-10 WO claimed
EP-2705037-B1 SUBSTITUTED IMIDAZOPYRIDINES AND IMIDAZOPYRIDAZINES AND USE THEREOF BAYER IP GMBH (DE) 2016-06-22 EP claimed
EP-2699578-B1 FLUOROALKYL-SUBSTITUTED PYRAZOLOPYRIDINES AND USE THEREOF BAYER IP GMBH (DE) 2016-04-20 EP claimed
EP-1768210-B1 Additives for overcharge protection in electrochemical cells AIR PROD & CHEM (US) 2015-04-29 EP claimed
EP-2635577-B1 SUBSTITUTED 6-FLUORO-1H-PYRAZOLO[4,3-B]PYRIDINES AND USE THEREOF BAYER IP GMBH (DE) 2014-10-01 EP claimed
WO-2024207638-A1 METHOD FOR PREPARING HYDROFLUOROCARBONS AND METHOD FOR PREPARING FLUORINE-CONTAINING ALKYNES 泉州宇极新材料科技有限公司 2024-10-10 WO disclosed
US-9465234-B2 Photochromic materials having extended pi-conjugated systems and compositions and articles including the same JOHNSON & JOHNSON VISION CARE, INC. (US) 2016-10-11 US disclosed
US-20150301357-A1 PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME JOHNSON & JOHNSON VISION CARE (US) 2015-10-22 US disclosed
US-9097916-B2 Photochromic materials having extended pi-conjugated systems and compositions and articles including the same JOHNSON & JOHNSON VISION CARE, INC. (US) 2015-08-04 US disclosed
US-20140225049-A1 PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2014-08-14 US disclosed
US-8741188-B2 Ophthalmic devices comprising photochromic materials having extended pi-conjugated systems JOHNSON & JOHNSON VISION CARE, INC. (US) 2014-06-03 US disclosed
US-8535551-B2 Plasma etching method ZEON CORPORATION (JP) 2013-09-17 US disclosed
WO-2012030518-A1 PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME TRANSITIONS OPTICAL, INC. (US) 2012-03-08 WO disclosed
US-20110049445-A1 PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME JOHNSON & JOHNSON VISION CARE, INC. 2011-03-03 US disclosed
US-20110042629-A1 PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME TRANSITIONS OPTICAL, INC. (US) 2011-02-24 US disclosed
US-20100264116-A1 PLASMA ETCHING METHOD ZEON CORPORATION (JP) 2010-10-21 US disclosed
EP-2194569-A1 PLASMA ETCHING METHOD ZEON CORPORATION (JP) 2010-06-09 EP disclosed
US-20060266976-A1 Compositions comprising bromofluoro-olefins and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2006-11-30 US disclosed
US-6569404-B1 Aqueous colloidal suspension, dispersed phase is gas microbubbles of perfluoropropane, perfluorobutane, perfluoropentane, perfluorohexane or sulfur hexafluoride; fluorinated amphiphile for stabilizing microbubbles AMERSHAM HEALTH A/S (NO) 2003-05-27 US disclosed
US-6245319-B1 Colloidal dispersions of perfluoropentane SONUS PHARMACEUTICALS, INC. 2001-06-12 US disclosed