SCHEMBL6358197

SCHEMBL6358197

C#CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL672488 1.00 LMNA (0.38) LMNATHRB
SCHEMBL10826755 1.00 LMNA (0.38) LMNATHRB
SCHEMBL31135124 1.00 LMNA (0.38) LMNATHRB
SCHEMBL5188413 0.97 LMNA (0.33) LMNA
SCHEMBL10826113 0.90
SCHEMBL10826142 0.90
SCHEMBL10826125 0.90
SCHEMBL2864416 0.87
Ethyne SCHEMBL10826121 0.87
SCHEMBL10826124 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240166658-A1 PORPHYRIN DERIVATIVES AND USES THEREOF UNIVERSITY OF TASMANIA (AU) 2024-05-23 US disclosed
EP-4298101-A1 PORPHYRIN DERIVATIVES AND USES THEREOF University Of Tasmania (AU) 2024-01-03 EP disclosed
WO-2022178593-A1 PORPHYRIN DERIVATIVES AND USES THEREOF UNIVERSITY OF TASMANIA (AU) 2022-09-01 WO disclosed
US-20050272599-A1 Mold release layer HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2005-12-08 US disclosed
US-5698169-A USING DICARBOLLIDE OR DICARBAEXTRANIDE COMPLEX; ION EXCHANGING COREMETALS RESEARCH, INC. (US) 1997-12-16 US disclosed
WO-1996039702-A2 METHODS AND AGENTS FOR THE EXTRACTION OF CESIUM AND STRONTIUM FROM NUCLEAR WASTE COREMETALS RESEARCH, INC. (US) 1996-12-12 WO disclosed
US-3983179-A BLOOD OXYGEN TRANSPORTS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166658-A1 PORPHYRIN DERIVATIVES AND USES THEREOF PFAS, PCBP1, FGR LMNA 4166/4885THRB 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.