Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ACP3 | P15309 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 3/20 | 0.47 |
| ▸ | GRM6 | O15303 | 3/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229711 | 0.87 | KMT2A (0.54) | SMN1; SMN2L3MBTL1HTTHPGDMEN1 | |
| SCHEMBL1983563 | 0.83 | L3MBTL1 (0.64) | SMN1; SMN2L3MBTL1HTTHPGDMEN1 | |
| SCHEMBL2367944 | 0.83 | L3MBTL1 (0.64) | SMN1; SMN2L3MBTL1HTTHPGDMEN1 | |
| SCHEMBL6743779 | 0.82 | L3MBTL1 (0.62) | SMN1; SMN2L3MBTL1HTTHPGDMEN1 | |
| SCHEMBL7110594 | 0.82 | L3MBTL1 (0.62) | SMN1; SMN2L3MBTL1HTTHPGDMEN1 | |
| SCHEMBL2234292 | 0.82 | L3MBTL1 (0.62) | SMN1; SMN2L3MBTL1HTTHPGDMEN1 | |
| SCHEMBL6745214 | 0.82 | L3MBTL1 (0.62) | SMN1; SMN2L3MBTL1HTTHPGDMEN1 | |
| SCHEMBL9154689 | 0.82 | L3MBTL1 (0.62) | SMN1; SMN2L3MBTL1HTTHPGDMEN1 | |
| SCHEMBL31376571 | 0.82 | L3MBTL1 (0.62) | SMN1; SMN2L3MBTL1HTTHPGDMEN1 | |
| Ammonia Solution, Strong SCHEMBL8975868 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1HTTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004057-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C Research Laboratories (KR) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014196793-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C RESEARCH LABORATORIES (KR) | 2014-12-11 | — | — | WO | disclosed |