Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ACP3 | P15309 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8867125 | 0.91 | CYP2D6 (0.52) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| Fumaric Acid SCHEMBL8866686 | 0.91 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| Formamide SCHEMBL8868988 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| Fumaric Acid SCHEMBL8866888 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL16396155 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL7008328 | 0.81 | KMT2A (0.55) | SMN1; SMN2HTTKMT2AMEN1CYP2C19 | |
| SCHEMBL18896279 | 0.80 | KMT2A (0.58) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL21200551 | 0.78 | L3MBTL1 (0.61) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL2878386 | 0.78 | L3MBTL1 (0.61) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL11810361 | 0.78 | KMT2A (0.57) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539120-A | Arylalkyl-amines having anticonvulsant and neuroprotective properties | AGENCE SPATIALE EUROPEENNE (FR) | 1996-07-23 | — | — | US | claimed |
| EP-0356035-B1 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | ASTRA AB (SE) | 1996-03-13 | — | — | EP | claimed |
| WO-1991011995-A1 | ARYLALKYL-AMINES AND -AMIDES HAVING ANTICONVULSANT AND NEUROPROTECTIVE PROPERTIES | FISONS CORPORATION (US) | 1991-08-22 | — | — | WO | claimed |
| EP-0356035-A2 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | Astra Aktiebolag (SE) | 1990-02-28 | — | — | EP | claimed |