Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666880 | 0.81 | DPP4 (0.33) | HTR2AHTR2CCHRM5CHRM3 | |
| SCHEMBL30335980 | 0.81 | CHRM5 (0.33) | CHRM5CHRM3 | |
| SCHEMBL510279 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27667001 | 0.75 | — | — | |
| Methane SCHEMBL16346850 | 0.75 | — | — | |
| SCHEMBL17477707 | 0.73 | GBA1 (0.37) | — | |
| SCHEMBL15549842 | 0.72 | — | — | |
| SCHEMBL1255721 | 0.72 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL25232214 | 0.71 | OPRM1 (0.32) | — | |
| SCHEMBL510150 | 0.71 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022194-A1 | INHIBITORS OF LEUKOTRIENE PRODUCTION | Boehringer Ingelheim International GmbH (DE) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015009611-A1 | INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-01-22 | — | — | WO | disclosed |