Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5156687 | 0.85 | SLC6A9 (0.41) | DPP4HTR2C | |
| SCHEMBL28129002 | 0.85 | — | — | |
| SCHEMBL27841937 | 0.85 | — | — | |
| SCHEMBL28131298 | 0.85 | — | — | |
| SCHEMBL5900537 | 0.84 | DPP4 (0.32) | DPP4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL28060538 | 0.84 | SLC6A9 (0.40) | DPP4HTR2C | |
| Hydrochloric Acid SCHEMBL3182976 | 0.82 | DPP4 (0.34) | DPP4CHRM5CHRM3KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL3182984 | 0.82 | DPP4 (0.34) | DPP4CHRM5CHRM3KDM4EMAPT | |
| SCHEMBL16397368 | 0.81 | HTR2A (0.32) | HTR2AHTR2CCHRM5CHRM3 | |
| SCHEMBL21649396 | 0.81 | CHRM5 (0.33) | DPP4HTR2CCHRM5CHRM3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485728-A1 | WNT PATHWAY ANTAGONISTS | Siena Biotech S.p.a. (IT) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011042145-A1 | WNT PATHWAY ANTAGONISTS | SIENA BIOTECH S.P.A. (IT) | 2011-04-14 | — | — | WO | disclosed |