Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.73 |
| ▸ | ALPI | P09923 | 1/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.73 |
| ▸ | XIAP | P98170 | 1/20 | 0.73 |
| ▸ | NOS3 | P29474 | 3/20 | 0.55 |
| ▸ | NOS1 | P29475 | 3/20 | 0.55 |
| ▸ | NOS2 | P35228 | 3/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.54 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL16397405 | 1.00 | SLC7A5 (0.73) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL288377 | 0.93 | SLC7A5 (0.60) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL288832 | 0.93 | SLC7A5 (0.60) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL385780 | 0.93 | SLC7A5 (0.60) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL29701247 | 0.93 | SLC7A5 (0.60) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL29069525 | 0.90 | SLC7A5 (0.85) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL1507755 | 0.90 | SLC7A5 (0.85) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL23159186 | 0.86 | SLC7A5 (1.00) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL385804 | 0.86 | SLC7A5 (1.00) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL15671104 | 0.86 | SLC7A5 (1.00) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022220-A1 | PROTEASE-RESISTANT PEPTIDE LIGANDS | North Carolina State University (US) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015009701-A1 | PROTEASE-RESISTANT PEPTIDE LIGANDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-01-22 | — | — | WO | disclosed |