SCHEMBL1639787

SCHEMBL1639787

CO[Si](C)(OC)c1ccc(-c2ccccc2)c([Si](C)(OC)OC)c1[Si](C)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SQOR Q9Y6N5 2/20 0.33
EGFR P00533 1/20 0.33
MAPT P10636 5/20 0.32
LMNA P02545 1/20 0.32
NPC1 O15118 4/20 0.32
RAB9A P51151 4/20 0.32
TDO2 P48775 2/20 0.32
ALDH1A1 P00352 4/20 0.31
MEN1 O00255 4/20 0.31
KMT2A Q03164 4/20 0.31
KDM4E B2RXH2 4/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
TP53 P04637 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
PIN1 Q13526 1/20 0.31
TSHR P16473 1/20 0.31
ATM Q13315 1/20 0.31
AKT1 P31749 1/20 0.31
AKT2 P31751 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1639810 0.86 MAPT (0.35) SQORMAPTLMNANPC1RAB9A
SCHEMBL1639792 0.78 KDM4E (0.33) LMNANPC1RAB9ATDO2ALDH1A1
SCHEMBL7186109 0.77 MAPT (0.38) SQORMAPTLMNANPC1RAB9A
SCHEMBL1638002 0.75 TDO2 (0.35) SQORMAPTLMNANPC1RAB9A
SCHEMBL1637771 0.73 SQOR (0.34) SQOREGFRMAPTMEN1KMT2A
SCHEMBL1639909 0.72
SCHEMBL1639784 0.70
SCHEMBL1639884 0.69 MAPT (0.40) MAPTRAB9AALDH1A1MEN1KMT2A
SCHEMBL1639954 0.69 CA4 (0.36) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL30473475 0.69 CA4 (0.36) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed