SCHEMBL1639792

SCHEMBL1639792

CCO[Si](C)(OCC)c1ccc(-c2ccccc2)c([Si](C)(OCC)OCC)c1[Si](C)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
MAPK10 P53779 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
NOTUM Q6P988 1/20 0.30
TDO2 P48775 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1639728 0.87 PDCD1 (0.34) KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL27599920 0.80 ALDH1A1 (0.37) KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL1639787 0.78 SQOR (0.33) KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL1639899 0.75 SOAT1 (0.33) KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL1639207 0.75 CYP1A2 (0.34)
SCHEMBL1639789 0.73
SCHEMBL30473468 0.72 ALDH1A1 (0.32) KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL1638005 0.72 ALDH1A1 (0.32) KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL1639799 0.72 ALDH1A1 (0.35) KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL1639726 0.71 ALDH1A1 (0.34) KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed