Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20392659 | 1.00 | ERN1 (0.35) | ERN1CYP1A1CYP1A2CYP1B1KDM4E | |
| SCHEMBL17734387 | 0.92 | HTR2C (0.33) | CYP1A1CYP1A2CYP1B1KDM4EPDE4B | |
| SCHEMBL20392604 | 0.92 | HTR2C (0.33) | CYP1A1CYP1A2CYP1B1KDM4EPDE4B | |
| SCHEMBL17734392 | 0.91 | PTGS2 (0.33) | ERN1ALDH1A1 | |
| SCHEMBL20392797 | 0.91 | PTGS2 (0.33) | ERN1ALDH1A1 | |
| SCHEMBL17734393 | 0.90 | ERN1 (0.34) | ERN1CYP1A1CYP1A2CYP1B1CA1 | |
| SCHEMBL20392662 | 0.90 | ERN1 (0.34) | ERN1CYP1A1CYP1A2CYP1B1CA1 | |
| SCHEMBL17734390 | 0.86 | CYP1A1 (0.34) | CYP1A1CYP1A2CYP1B1HCRTR1HCRTR2 | |
| SCHEMBL16398611 | 0.84 | AHR (0.31) | — | |
| SCHEMBL17734408 | 0.83 | ALDH1A1 (0.31) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10375956-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2019-08-13 | — | — | US | disclosed |
| US-10375956-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2019-08-13 | — | — | US | disclosed |
| EP-3004063-B1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-07-18 | — | — | EP | disclosed |
| EP-3004063-B1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-07-18 | — | — | EP | disclosed |
| US-20160128326-A1 | Herbicidally Active 2-(Substituted-Phenyl)-Cyclopentane-1,3-Dione Compounds and Derivatives Thereof | SYNGENTA LIMITED (GB) | 2016-05-12 | — | — | US | disclosed |
| US-20160128326-A1 | Herbicidally Active 2-(Substituted-Phenyl)-Cyclopentane-1,3-Dione Compounds and Derivatives Thereof | SYNGENTA LIMITED (GB) | 2016-05-12 | — | — | US | disclosed |
| EP-3004063-A1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | Syngenta Limited (GB) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014195327-A1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LIMITED (GB) | 2014-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160128326-A1 | Herbicidally Active 2-(Substituted-Phenyl)-Cyclopentane-1,3-Dione Compounds and Derivatives Thereof | DDT, HDHD5, CNPY2 | ERN1 2026/4885CYP1A1 54/4885CYP1A2 162/4885 |
| US-10375956-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | DDT, HDHD5, CNPY2 | ERN1 2026/4885CYP1A1 54/4885CYP1A2 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.