SCHEMBL16398781

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16398777	1.00	ERBB2 (0.45)	ERBB2CYP11B1CYP11B2CTSSNFE2L2
	SCHEMBL16399536	0.90	ERBB2 (0.50)	ERBB2CTSSNFE2L2CTSKIDO1
	SCHEMBL17969159	0.90	ERBB2 (0.50)	ERBB2CTSSNFE2L2CTSKIDO1
	SCHEMBL16399518	0.86	ERBB2 (0.49)	ERBB2CTSSNFE2L2CTSKPRMT6
	SCHEMBL16399521	0.86	ERBB2 (0.49)	ERBB2CTSSNFE2L2CTSKPRMT6
	SCHEMBL16399271	0.85	ERBB2 (0.46)	ERBB2CTSSNFE2L2CTSKPRMT6
	SCHEMBL16399272	0.85	ERBB2 (0.46)	ERBB2CTSSNFE2L2CTSKPRMT6
	SCHEMBL16399390	0.83	ERBB2 (0.45)	ERBB2CTSSNFE2L2CTSKIDO1
	SCHEMBL16399392	0.83	ERBB2 (0.45)	ERBB2CTSSNFE2L2CTSKIDO1
	SCHEMBL31622851	0.83	ERBB2 (0.45)	ERBB2CTSSNFE2L2CTSKIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.