SCHEMBL1639890

SCHEMBL1639890

CCO[Si](C)(OCC)c1cc2ccccc2c([Si](C)(OCC)OCC)c1[Si](C)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 2/20 0.33
S1PR3 Q99500 1/20 0.33
NR1I2 O75469 1/20 0.33
CYP1A2 P05177 2/20 0.32
BTK Q06187 1/20 0.32
ABCB11 O95342 1/20 0.32
LMNA P02545 1/20 0.32
CYP2D6 P10635 1/20 0.32
SCN1A P35498 1/20 0.32
SCN2A Q99250 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SCN3A Q9NY46 1/20 0.32
KDM4E B2RXH2 2/20 0.32
ATM Q13315 1/20 0.32
ELANE P08246 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
HTR2A P28223 1/20 0.31
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1639799 0.82 ALDH1A1 (0.35) S1PR1S1PR3CYP1A2LMNATDP1
SCHEMBL1638822 0.78 ERN1 (0.34) CYP1A2TDP1KDM4EATMCYP2A6
SCHEMBL29444236 0.76 HPGD (0.39) S1PR1S1PR3CYP1A2LMNACYP2D6
SCHEMBL6850272 0.76 HPGD (0.39) S1PR1S1PR3CYP1A2LMNACYP2D6
SCHEMBL1639907 0.75 NR1I2 (0.33) NR1I2CYP1A2BTKABCB11LMNA
SCHEMBL15848306 0.75 NQO1 (0.35) S1PR1S1PR3NR1I2CYP1A2LMNA
SCHEMBL4099237 0.74 NR1I2 (0.40) NR1I2CYP1A2BTKLMNAKDM4E
SCHEMBL1638005 0.72 ALDH1A1 (0.32) KDM4EELANEMAPTTSHRALDH1A1
SCHEMBL30473468 0.72 ALDH1A1 (0.32) KDM4EELANEMAPTTSHRALDH1A1
SCHEMBL27773337 0.71 NR1I2 (0.38) NR1I2CYP1A2BTKABCB11LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed