Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748665 | 0.93 | NR1I2 (0.36) | NR1I2L3MBTL1HTR2AALDH1A1HSD17B10 | |
| SCHEMBL1639907 | 0.86 | NR1I2 (0.33) | NR1I2L3MBTL1HTR2AALDH1A1HSD17B10 | |
| SCHEMBL3350607 | 0.86 | GABRP (0.36) | L3MBTL1ALDH1A1CYP1A2KDM4EHPGD | |
| SCHEMBL16709834 | 0.82 | NR1I2 (0.30) | NR1I2 | |
| SCHEMBL27773337 | 0.81 | NR1I2 (0.38) | NR1I2L3MBTL1HTR2AALDH1A1HSD17B10 | |
| SCHEMBL1639321 | 0.80 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1HSD17B10CYP1A2CYP2A6 | |
| SCHEMBL28262655 | 0.80 | CYP1A2 (0.33) | NR1I2L3MBTL1HTR2AALDH1A1HSD17B10 | |
| SCHEMBL6697302 | 0.79 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1HSD17B10CYP2A6KDM4E | |
| SCHEMBL2352239 | 0.79 | CYP2A6 (0.35) | NR1I2L3MBTL1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL1929080 | 0.78 | TRPM4 (0.38) | NR1I2L3MBTL1HTR2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090246716-A1 | HIGH REFRACTIVE INDEX SOL-GEL COMPOSITION AND METHOD OF MAKING PHOTO-PATTERNED STRUCTURES ON A SUBSTRATE | NITTO DENKO CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20090246716-A1 | HIGH REFRACTIVE INDEX SOL-GEL COMPOSITION AND METHOD OF MAKING PHOTO-PATTERNED STRUCTURES ON A SUBSTRATE | NITTO DENKO CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| WO-2009120410-A2 | HIGH REFRACTIVE INDEX SOL-GEL COMPOSITION AND METHOD OF MAKING PHOTO-PATTERNED STRUCTURES ON A SUBSTRATE | NITTO DENKO CORPORATION (JP) | 2009-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246716-A1 | HIGH REFRACTIVE INDEX SOL-GEL COMPOSITION AND METHOD OF MAKING PHOTO-PATTERNED STRUCTURES ON A SUBSTRATE | SOS1, SOS2, MMS19 | NR1I2 592/4885L3MBTL1 2555/4885HTR2A 4419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.