SCHEMBL16398919

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16398917	1.00	HDAC2 (0.40)	HDAC2FBP1ALDH1A1MAPTKDM4E
	SCHEMBL16399388	0.88	KDM4E (0.39)	ALDH1A1MAPTKDM4ENPC1GLA
	SCHEMBL16399387	0.88	KDM4E (0.39)	ALDH1A1MAPTKDM4ENPC1GLA
	SCHEMBL16399071	0.87	TTK (0.39)	ALDH1A1MAPTKDM4ENPC1TTK
	SCHEMBL17969025	0.87	EGFR (0.33)	HDAC2
	SCHEMBL17969113	0.87	ERBB2 (0.37)	HDAC2ALDH1A1MAPTKDM4ENPC1
	SCHEMBL16399217	0.87	EGFR (0.33)	HDAC2
	SCHEMBL17969133	0.87	KDM4E (0.43)	ALDH1A1MAPTKDM4ENPC1POLB
	SCHEMBL17969010	0.87	ERBB2 (0.42)	HDAC2ALDH1A1MAPTKDM4ENPC1
	SCHEMBL17969114	0.87	ERBB2 (0.37)	HDAC2ALDH1A1MAPTKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.