SCHEMBL1640002

SCHEMBL1640002

O=C1NC(=O)N(Cc2ccccc2)C(=O)C1c1ccc(Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.49
CNR1 P21554 2/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
ELANE P08246 2/20 0.44
F2 P00734 1/20 0.42
PLG P00747 1/20 0.42
CTSG P08311 1/20 0.42
CMA1 P23946 1/20 0.42
CTRC Q99895 1/20 0.42
RAB9A P51151 1/20 0.41
EP300 Q09472 1/20 0.41
SMO Q99835 2/20 0.40
GSK3A P49840 1/20 0.40
GSK3B P49841 1/20 0.40
MGLL Q99685 1/20 0.40
MDM2 Q00987 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL66999 0.91 MEN1 (0.51) MEN1KMT2AALDH1A1ELANEF2
SCHEMBL1263711 0.90 MEN1 (0.50) MEN1KMT2AALDH1A1ELANEF2
SCHEMBL1264158 0.90 MEN1 (0.50) MEN1KMT2AALDH1A1ELANEF2
SCHEMBL1640000 0.87 ELANE (0.46) MEN1KMT2AALDH1A1MAPTELANE
SCHEMBL17717905 0.84 KMT2A (0.44) MEN1KMT2AALDH1A1MAPTELANE
SCHEMBL17717915 0.84 MEN1 (0.47) MEN1KMT2AALDH1A1MAPTELANE
SCHEMBL17717967 0.78 EP300 (0.50) MEN1KMT2AALDH1A1MAPTELANE
SCHEMBL15978121 0.77 LMNA (0.40) MEN1KMT2AALDH1A1MAPT
SCHEMBL17717953 0.77 EP300 (0.48) MEN1KMT2AALDH1A1MAPTELANE
SCHEMBL5268595 0.77 KMT2A (0.49) MEN1KMT2AALDH1A1MAPTELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10871597-B2 Polarizing plate, image display device, and polarizing plate protective film FUJIFILM CORPORATION (JP) 2020-12-22 US disclosed
US-10459290-B2 Optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2019-10-29 US disclosed
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device FUJIFILM CORPORATION (JP) 2019-10-29 US disclosed
US-10240033-B2 Optical film and method for manufacturing same, polarization plate, and liquid crystal display apparatus FUJIFILM CORPORATION (JP) 2019-03-26 US disclosed
US-20170322358-A1 POLARIZING PLATE, FRONT PANEL OF DISPLAY DEVICE, DISPLAY APPARATUS, SUBSTRATE OF TOUCH PANEL, RESISTIVE FILM-TYPE TOUCH PANEL, AND CAPACITANCE-TYPE TOUCH PANEL FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
US-20170322358-A1 POLARIZING PLATE, FRONT PANEL OF DISPLAY DEVICE, DISPLAY APPARATUS, SUBSTRATE OF TOUCH PANEL, RESISTIVE FILM-TYPE TOUCH PANEL, AND CAPACITANCE-TYPE TOUCH PANEL FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-9507067-B2 Polarizing plate and liquid crystal display device including the same FUJIFILM CORPORATION (JP) 2016-11-29 US disclosed
US-9507067-B2 Polarizing plate and liquid crystal display device including the same FUJIFILM CORPORATION (JP) 2016-11-29 US disclosed
US-20140242300-A1 POLARIZER, POLARIZING PLATE USING THE SAME, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD OF MANUFACTURING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2014-08-28 US disclosed
US-20140242300-A1 POLARIZER, POLARIZING PLATE USING THE SAME, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD OF MANUFACTURING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2014-08-28 US disclosed
US-20140242302-A1 LAMINATE, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD OF MANUFACTURING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2014-08-28 US disclosed
US-20140242302-A1 LAMINATE, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD OF MANUFACTURING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2014-08-28 US disclosed
US-20130189449-A1 POLARIZING PLATE, METHOD FOR PREPARING THE SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-07-25 US disclosed
US-20130189449-A1 POLARIZING PLATE, METHOD FOR PREPARING THE SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-07-25 US disclosed
US-20120088041-A1 Polarizer protective film, polarizer, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-12 US disclosed
US-20120088041-A1 Polarizer protective film, polarizer, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-12 US disclosed
US-20110134374-A1 PROTECTIVE FILM OF POLARIZER, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-06-09 US disclosed
US-20110134374-A1 PROTECTIVE FILM OF POLARIZER, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device NBAS, SSB, GNA15 PIM1 4012/4885CNR1 2329/4885MEN1 2124/4885
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 PIM1 4136/4885CNR1 2510/4885MEN1 2234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.