Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081377 | 0.71 | CA14 (0.34) | DGAT1HDAC6HDAC1HDAC2 | |
| SCHEMBL8737769 | 0.69 | HDAC6 (0.39) | DGAT1HDAC6HDAC1HDAC2 | |
| SCHEMBL761358 | 0.69 | HDAC6 (0.39) | DGAT1HDAC6HDAC1HDAC2 | |
| SCHEMBL28394 | 0.67 | HDAC6 (0.38) | DGAT1HDAC6HDAC1HDAC2 | |
| SCHEMBL478212 | 0.67 | CYP2C19 (0.32) | HDAC6HDAC1HDAC2 | |
| SCHEMBL23452708 | 0.67 | DGAT1 (0.43) | DGAT1HDAC6HDAC1HDAC2 | |
| SCHEMBL3266659 | 0.66 | CTSD (0.37) | DGAT1HDAC6HDAC1HDAC2 | |
| SCHEMBL13286079 | 0.66 | HDAC6 (0.37) | DGAT1HDAC6HDAC1HDAC2 | |
| SCHEMBL206709 | 0.66 | HDAC6 (0.37) | DGAT1HDAC6HDAC1HDAC2 | |
| SCHEMBL12096699 | 0.66 | HDAC6 (0.37) | DGAT1HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004084-B1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma AG (DE) | 2017-03-01 | — | — | EP | disclosed |
| EP-3004084-A1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma Aktiengesellschaft (DE) | 2016-04-13 | — | — | EP | disclosed |
| EP-3004095-A1 | TRIAZOLOPYRIDINES AS THROMBIN INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISEASES | Bayer Pharma Aktiengesellschaft (DE) | 2016-04-13 | — | — | EP | disclosed |
| EP-3004086-A1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma Aktiengesellschaft (DE) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014195244-A1 | TRIAZOLOPYRIDINES AS THROMBIN INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISEASES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-12-11 | — | — | WO | disclosed |
| WO-2014195230-A1 | SUBSTITUTED BENZOXAZOLES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-12-11 | — | — | WO | disclosed |
| WO-2014195231-A1 | SUBSTITUTED BENZOXAZOLES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-12-11 | — | — | WO | disclosed |