Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18341182 | 0.86 | ALDH1A1 (0.39) | ALDH1A1HSD17B10ABCB1MEN1KMT2A | |
| SCHEMBL2059285 | 0.68 | MAPK1 (0.39) | ALDH1A1ABCB1MEN1KMT2AKDM4E | |
| SCHEMBL2059287 | 0.68 | MAPK1 (0.39) | ALDH1A1ABCB1MEN1KMT2AKDM4E | |
| SCHEMBL2392433 | 0.67 | ALDH1A1 (0.40) | ALDH1A1HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL9358596 | 0.67 | ABCB1 (0.43) | ALDH1A1HSD17B10ABCB1MEN1KMT2A | |
| SCHEMBL9362699 | 0.66 | ALDH1A1 (0.44) | ALDH1A1HSD17B10ABCB1MEN1KMT2A | |
| SCHEMBL1189045 | 0.66 | ABCB1 (0.42) | ALDH1A1HSD17B10ABCB1MEN1KMT2A | |
| SCHEMBL17542008 | 0.65 | ABCB1 (0.43) | ABCB1MEN1KMT2AFUCA1TACR3 | |
| SCHEMBL28879326 | 0.65 | ABCB1 (0.43) | ABCB1MEN1KMT2AFUCA1TACR3 | |
| SCHEMBL18340961 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004086-A1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma Aktiengesellschaft (DE) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014195230-A1 | SUBSTITUTED BENZOXAZOLES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-12-11 | — | — | WO | disclosed |