Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362699 | 0.87 | ALDH1A1 (0.44) | ABCB1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL9358209 | 0.81 | LMNA (0.38) | CYP3A4TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL9358198 | 0.81 | CYP3A4 (0.41) | CYP3A4TSHRALDH1A1 | |
| SCHEMBL9003125 | 0.70 | ACHE (0.42) | CYP3A4TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL9358391 | 0.69 | TRPA1 (0.40) | — | |
| SCHEMBL9307823 | 0.67 | TSHR (0.49) | CYP3A4TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16400504 | 0.67 | ALDH1A1 (0.39) | ABCB1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL27690100 | 0.66 | TSHR (0.67) | CYP3A4TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL9358293 | 0.66 | ALDH1A1 (0.36) | CYP3A4MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL11694221 | 0.65 | MAPK1 (0.43) | CYP3A4TSHRMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518197-B1 | Piperidine derivatives | MITSUBISHI PETROCHEMICAL CO (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5260443-A | For polyolefin films | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5189172-A | Useful as photostabilizer or as intermediates for pharmaceuticals and agricultural chemicals | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0518197-A1 | Piperidine derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-16 | — | — | EP | disclosed |