Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652156 | 0.89 | RORC (0.41) | BACE1RORCMEN1KMT2A | |
| SCHEMBL16409338 | 0.89 | RORC (0.41) | BACE1RORCMEN1KMT2A | |
| SCHEMBL20555488 | 0.84 | SRD5A1 (0.47) | BACE1SRD5A1SMYD2NPC1RAB9A | |
| SCHEMBL31624781 | 0.81 | SMYD2 (0.36) | BACE1SRD5A1KMT2ASMYD2 | |
| SCHEMBL20555296 | 0.81 | NPC1 (0.37) | BACE1SRD5A1MEN1KMT2ASMYD2 | |
| SCHEMBL16400757 | 0.81 | BACE1 (0.36) | BACE1MEN1KMT2ACHRM3 | |
| SCHEMBL30065370 | 0.79 | MEN1 (0.38) | BACE1MEN1KMT2ACHRM3 | |
| SCHEMBL517028 | 0.78 | RBP4 (0.38) | BACE1RORCMEN1KMT2ACHRM3 | |
| SCHEMBL1444038 | 0.77 | BACE1 (0.43) | BACE1SMYD2 | |
| SCHEMBL26985459 | 0.77 | MEN1 (0.41) | RORCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022192-A1 | PIPERIDINYL INDOLE DERIVATIVES AND THEIR USE AS COMPLEMENT FACTOR B INHIBITORS | Novartis AG (CH) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015009616-A1 | PIPERIDINYL INDOLE DERIVATIVES AND THEIR USE AS COMPLEMENT FACTOR B INHIBITORS | NOVARTIS AG (CH) | 2015-01-22 | — | — | WO | disclosed |