Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.43 |
| ▸ | AMPD2 | Q01433 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16399740 | 0.90 | ELANE (0.44) | ELANECTSGPRTN3AMPD2ALDH1A1 | |
| SCHEMBL16401374 | 0.77 | ELANE (0.43) | ELANECTSGPRTN3AMPD2ALDH1A1 | |
| SCHEMBL16399447 | 0.77 | AMPD2 (0.44) | ELANECTSGPRTN3AMPD2ALDH1A1 | |
| SCHEMBL17685971 | 0.77 | ELANE (0.38) | ELANECTSGPRTN3AMPD2ALDH1A1 | |
| SCHEMBL16400524 | 0.77 | ELANE (0.44) | ELANECTSGPRTN3AMPD2ALDH1A1 | |
| SCHEMBL16400528 | 0.72 | MEN1 (0.38) | ELANECTSGPRTN3AMPD2ALDH1A1 | |
| SCHEMBL16401189 | 0.69 | KMT2A (0.46) | ELANECTSGPRTN3GAAL3MBTL1 | |
| SCHEMBL2074739 | 0.69 | ALDH1A1 (0.42) | ELANECTSGPRTN3AMPD2ALDH1A1 | |
| SCHEMBL16400061 | 0.68 | ELANE (0.42) | ELANECTSGPRTN3ALDH1A1GAA | |
| SCHEMBL18569737 | 0.68 | BRD4 (0.41) | ELANECTSGPRTN3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004086-A1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma Aktiengesellschaft (DE) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014195230-A1 | SUBSTITUTED BENZOXAZOLES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-12-11 | — | — | WO | disclosed |