SCHEMBL16401460

SCHEMBL16401460

CC(C)(C)[Si](C)(C)OOC(=O)CCCC#N

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27321457 0.80 DGKA (0.37) MEN1KMT2A
SCHEMBL31053791 0.78 TSHR (0.47) MEN1KMT2A
SCHEMBL31039401 0.77 PTPN7 (0.51) MEN1KMT2A
SCHEMBL9842180 0.77 DGKA (0.47) MEN1KMT2A
SCHEMBL31386976 0.75 ALDH1A1 (0.43)
Butane SCHEMBL1155320 0.74 TSHR (0.43) MEN1KMT2A
SCHEMBL11618915 0.73 MEN1 (0.32) MEN1KMT2A
SCHEMBL9681593 0.73 ALDH1A1 (0.33)
SCHEMBL4921825 0.71 HPGD (0.34)
SCHEMBL31537920 0.71 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3022213-A1 PROCESS FOR THE PREPARATION OF ROSUVASTATIN CALCIUM AND PREPARATION OF ITS NOVEL INTERMEDIATES Suven Life Sciences Limited (IN) 2016-05-25 EP claimed
WO-2015008294-A1 PROCESS FOR THE PREPARATION OF ROSUVASTATIN CALCIUM AND PREPARATION OF ITS NOVEL INTERMEDIATES SUVEN LIFE SCIENCES LIMITED (IN) 2015-01-22 WO claimed