SCHEMBL9681593

SCHEMBL9681593

C=CC(=O)CCCC(=O)OO[Si](C)(C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31053791 0.80 TSHR (0.47) ALDH1A1LMNATSHR
SCHEMBL27321457 0.78 DGKA (0.37) ALDH1A1LMNATSHR
Butane SCHEMBL1155320 0.76 TSHR (0.43) ALDH1A1TSHR
SCHEMBL9842180 0.76 DGKA (0.47) ALDH1A1LMNATSHR
SCHEMBL31386976 0.74 ALDH1A1 (0.43) ALDH1A1LMNATSHR
SCHEMBL14334628 0.74 HSP90AA1 (0.33) TSHR
SCHEMBL4921825 0.73 HPGD (0.34)
SCHEMBL16401460 0.73 MEN1 (0.30)
SCHEMBL14194004 0.73 TSHR (0.37) ALDH1A1TSHR
SCHEMBL8624294 0.71 TSHR (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0494120-A1 HMG-CoA reductase inhibitors BRITISH BIO-TECHNOLOGY LIMITED (GB) 1992-07-08 EP disclosed