SCHEMBL16401468

SCHEMBL16401468

Cc1cccc(C)c1NC(=O)NS/N=C/c1ccc2c(c1)CCc1c-2nnn1-c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
SMURF1 Q9HCE7 3/20 0.32
SMURF2 Q9HAU4 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16401173 0.93 PFKFB3 (0.32) L3MBTL1SMURF1SMURF2
SCHEMBL16400813 0.88 MAPT (0.35) SMURF1SMURF2
SCHEMBL16401471 0.83 LMNA (0.43)
SCHEMBL16401470 0.83 LMNA (0.43)
SCHEMBL16401142 0.82 MAPT (0.34) SMURF1SMURF2
SCHEMBL17798953 0.81 MAPT (0.34) SMURF1SMURF2
SCHEMBL16401571 0.81 SMURF2 (0.39) SMURF1SMURF2
SCHEMBL16401160 0.80 TRPV1 (0.33)
SCHEMBL16401310 0.79 SMURF2 (0.41) SMURF1SMURF2
SCHEMBL19304575 0.79 L3MBTL1 (0.34) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3022185-B1 PESTICIDE COMPOUNDS BASF SE (DE) 2017-09-06 EP claimed
US-9497970-B2 Pesticide compounds BASF SE (DE) 2016-11-22 US claimed
US-20160157491-A1 Pesticide Compounds BASF SE (DE) 2016-06-09 US claimed
EP-3022185-A1 PESTICIDE COMPOUNDS BASF SE (DE) 2016-05-25 EP claimed
WO-2015007682-A1 PESTICIDE COMPOUNDS BASF SE (DE) 2015-01-22 WO claimed
EP-3022185-B1 PESTICIDE COMPOUNDS BASF SE (DE) 2017-09-06 EP disclosed
US-9497970-B2 Pesticide compounds BASF SE (DE) 2016-11-22 US disclosed
US-20160157491-A1 Pesticide Compounds BASF SE (DE) 2016-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160157491-A1 Pesticide Compounds C1R, C1S, CBR3 L3MBTL1 705/4885SMURF1 3269/4885SMURF2 3631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.