SCHEMBL16401520

SCHEMBL16401520

Cc1ccc(S(=O)(=O)S(=O)(=O)NC(Cc2ccccc2)C(=O)C(=O)CCl)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 5/20 0.47
TDP1 Q9NUW8 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CTSL P07711 1/20 0.44
MMP2 P08253 6/20 0.44
ADAMTS4 O75173 1/20 0.44
NPY5R Q15761 1/20 0.44
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 2/20 0.43
ADAMTS5 Q9UNA0 1/20 0.43
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ITGB1 P05556 1/20 0.42
ITGA4 P13612 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4504106 1.00 MMP9 (0.47) MMP9TDP1POLBGAACA2
SCHEMBL2213327 0.88 MMP9 (0.60) MMP9TDP1POLBGAACA2
SCHEMBL669507 0.88 MMP9 (0.60) MMP9TDP1POLBGAACA2
SCHEMBL11146335 0.81 GAA (0.51) MMP9TDP1POLBGAACA2
SCHEMBL1023659 0.79 GAA (0.47) MMP9GAAALDH1A1MAPTTHRB
SCHEMBL1469951 0.77 POLB (0.52) MMP9POLBGAAMMP2ADAMTS4
SCHEMBL27488248 0.77 POLB (0.52) MMP9POLBGAAMMP2ADAMTS4
Tpck SCHEMBL927265 0.77 MMP9 (0.61) MMP9TDP1POLBGAACA2
Tpck SCHEMBL441444 0.77 MMP9 (0.61) MMP9TDP1POLBGAACA2
SCHEMBL433895 0.75 MMP9 (0.69) MMP9TDP1POLBCA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105518129-B Attenuated influenza vaccines and uses thereof 罗切斯特大学 2020-04-28 CN disclosed
EP-3022298-B1 ATTENUATED INFLUENZA VACCINES AND USES THEREOF UNIV ROCHESTER (US) 2019-06-19 EP disclosed
US-10323231-B2 Attenuated influenza vaccines and uses thereof UNIVERSITY OF ROCHESTER (US) 2019-06-18 US disclosed
US-20180223261-A1 ATTENUATED INFLUENZA VACCINES AND USES THEREOF UNIVERSITY OF ROCHESTER (US) 2018-08-09 US disclosed
US-9878032-B2 Attenuated influenza vaccines and uses thereof UNIVERSITY OF ROCHESTER (US) 2018-01-30 US disclosed
WO-2016172588-A1 ATTENUATED INFLUENZA VACCINES AND USES THEREOF COX ANDREW (US) 2016-10-27 WO disclosed
EP-3022298-A1 ATTENUATED INFLUENZA VACCINES AND USES THEREOF University Of Rochester (US) 2016-05-25 EP disclosed
US-20160136260-A1 ATTENUATED INFLUENZA VACCINES AND USES THEREOF UNIVERSITY OF ROCHESTER (US) 2016-05-19 US disclosed
US-20150224187-A1 ATTENUATED INFLUENZA VACCINES AND USES THEREOF NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2015-08-13 US disclosed
WO-2015010073-A1 ATTENUATED INFLUENZA VACCINES AND USES THEREOF UNIVERSITY OF ROCHESTER (US) 2015-01-22 WO disclosed