SCHEMBL4504106

SCHEMBL4504106

Cc1ccc(S(=O)(=O)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)C(=O)CCl)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 5/20 0.47
TDP1 Q9NUW8 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CTSL P07711 1/20 0.44
MMP2 P08253 6/20 0.44
ADAMTS4 O75173 1/20 0.44
NPY5R Q15761 1/20 0.44
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 2/20 0.43
ADAMTS5 Q9UNA0 1/20 0.43
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ITGB1 P05556 1/20 0.42
ITGA4 P13612 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16401520 1.00 MMP9 (0.47) MMP9TDP1POLBGAACA2
SCHEMBL2213327 0.88 MMP9 (0.60) MMP9TDP1POLBGAACA2
SCHEMBL669507 0.88 MMP9 (0.60) MMP9TDP1POLBGAACA2
SCHEMBL11146335 0.81 GAA (0.51) MMP9TDP1POLBGAACA2
SCHEMBL1023659 0.79 GAA (0.47) MMP9GAAALDH1A1MAPTTHRB
SCHEMBL1469951 0.77 POLB (0.52) MMP9POLBGAAMMP2ADAMTS4
SCHEMBL27488248 0.77 POLB (0.52) MMP9POLBGAAMMP2ADAMTS4
Tpck SCHEMBL927265 0.77 MMP9 (0.61) MMP9TDP1POLBGAACA2
Tpck SCHEMBL441444 0.77 MMP9 (0.61) MMP9TDP1POLBGAACA2
SCHEMBL433895 0.75 MMP9 (0.69) MMP9TDP1POLBCA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692344-A1 SELF-AMPLIFYING RNA CONSTRUCT AND USE THEREOF Microuni Co., Ltd. (KR) 2026-02-11 EP disclosed
US-20260034205-A1 MODIFIED LIVE ATTENUATED FLU VIRUS VACCINES AND USES THEREOF US AGRICULTURE (US) 2026-02-05 US disclosed
US-12421301-B2 Anti-influenza neuraminidase monoclonal antibodies and uses thereof UNIVERSITY OF ROCHESTER (US) 2025-09-23 US disclosed
US-20250290095-A1 Trans-Replicating RNA BioNTech SE (DE) 2025-09-18 US disclosed
US-20250250548-A1 METHODS AND COMPOSITIONS FOR TREATING NEGATIVE-SENSE SINGLE-STRANDED RNA VIRUS THE UNIVERSITY OF CHICAGO (US) 2025-08-07 US disclosed
US-12370236-B2 Method and combination for the suppression of COVID-19 virus NATIONAL TSING HUA UNIVERSITY (TW) 2025-07-29 US disclosed
US-12338448-B2 Trans-replicating RNA TRON-TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ (DE) 2025-06-24 US disclosed
US-12227769-B2 Methods and compositions for treating negative-sense single-stranded RNA virus THE UNIVERSITY OF CHICAGO (US) 2025-02-18 US disclosed
WO-2024181753-A1 SELF-AMPLIFYING RNA CONSTRUCT AND USE THEREOF 주식회사 마이크로유니 2024-09-06 WO disclosed
US-20240254205-A1 ANTI-INFLUENZA NEURAMINIDASE MONOCLONAL ANTIBODIES AND USES THEREOF UNIVERSITY OF ROCHESTER (US) 2024-08-01 US disclosed
WO-2015196150-A2 MUTATIONS THAT CONFER GENETIC STABILITY TO ADDITIONAL GENES IN INFLUENZA VIRUSES WISCONSIN ALUMNI RESEARCH FOUNDATION (WARF) (US) 2015-12-23 WO disclosed
US-20150232454-A1 THERAPEUTIC HYDROXYPYRIDINONES, HYDROXYPYRIMIDINONES AND HYDROXYPYRIDAZINONES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-08-20 US disclosed
US-20150224187-A1 ATTENUATED INFLUENZA VACCINES AND USES THEREOF NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2015-08-13 US disclosed
WO-2015010073-A1 ATTENUATED INFLUENZA VACCINES AND USES THEREOF UNIVERSITY OF ROCHESTER (US) 2015-01-22 WO disclosed
WO-2014043252-A2 THERAPEUTIC HYDROXYPYRIDINONES, HYDROXYPYRIMIDINONES AND HYDROXYPYRIDAZINONES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2014-03-20 WO disclosed
US-7592169-B2 Methods and compositions for treatment and prevention of HSV-2 infections and conditions MEDIMMUNE, LLC (US) 2009-09-22 US disclosed
US-20050112142-A1 Methods and compositions for treatment and prevention of HSV-2 infections and conditions MEDIMMUNE, LLC 2005-05-26 US disclosed
US-5922328-A HERPES SIMPLEX AVIRON (US) 1999-07-13 US disclosed
WO-1997009999-A9 METHODS AND COMPOSITIONS FOR TREATMENT OF HSV-2 INFECTIONS AND CONDITIONS 1997-11-06 WO disclosed
WO-1997009999-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF HSV-2 INFECTIONS AND CONDITIONS AVIRON (US) 1997-03-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150232454-A1 THERAPEUTIC HYDROXYPYRIDINONES, HYDROXYPYRIMIDINONES AND HYDROXYPYRIDAZINONES XDH, DPYD, DHX15 MMP9 2501/4885TDP1 101/4885POLB 1717/4885
US-20260034205-A1 MODIFIED LIVE ATTENUATED FLU VIRUS VACCINES AND USES THEREOF IL2RA, IL36G, TRRAP MMP9 4242/4885TDP1 3699/4885POLB 3966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.