Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 4/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401926 | 0.81 | CA5A (0.57) | HDAC1ALDH1A1MAPTPKML3MBTL1 | |
| SCHEMBL28794120 | 0.81 | HDAC1 (0.58) | HDAC1ALDH1A1MAPTPKML3MBTL1 | |
| SCHEMBL16401309 | 0.80 | TYR (0.58) | L3MBTL1KDM1AROCK2PIM1GSK3B | |
| SCHEMBL16401305 | 0.76 | CYP19A1 (0.47) | ALDH1A1MAPTCYP19A1HSP90AB1KCNMA1 | |
| SCHEMBL29113895 | 0.76 | ALDH1A1 (0.47) | HDAC1ALDH1A1MAPTPKML3MBTL1 | |
| SCHEMBL10434376 | 0.76 | ALDH1A1 (0.47) | HDAC1ALDH1A1MAPTPKML3MBTL1 | |
| SCHEMBL16401451 | 0.75 | CYP19A1 (0.61) | CYP19A1HSP90AB1NPC1RAB9A | |
| SCHEMBL9858144 | 0.75 | CA5A (0.55) | HDAC1ALDH1A1MAPTPKML3MBTL1 | |
| SCHEMBL16401620 | 0.75 | CD74 (0.46) | ROCK2HSP90AB1 | |
| SCHEMBL9857405 | 0.74 | CA5A (0.72) | HDAC1ALDH1A1MAPTPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |