SCHEMBL1640341

SCHEMBL1640341

CC(C)(C)C1CC(CI)CCN1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.31
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3504553 0.88
SCHEMBL1810381 0.85 NR1H2 (0.33) RIPK1DPP4
SCHEMBL18322450 0.85 RIPK1 (0.34) RIPK1DPP4
SCHEMBL3586527 0.84 RIPK1 (0.31) RIPK1DPP4
SCHEMBL482006 0.84 NCF1 (0.36) RIPK1DPP4
SCHEMBL15864996 0.84 SMYD3 (0.30)
SCHEMBL619575 0.83 TYMP (0.33) RIPK1DPP4
SCHEMBL28366570 0.82 NR1H2 (0.38)
SCHEMBL7990391 0.81 PREP (0.31)
SCHEMBL2525440 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105705488-B Compounds of acetylcholinesterase inhibitors and 5-hydroxytryptamine receptor 4 agonists, process for their preparation and pharmaceutical compositions thereof 卡昂大学 2020-03-24 CN disclosed
US-20110098296-A1 Thiazole And Oxazole Kinase Inhibitors GLAXOSMITHKLINE LLC 2011-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098296-A1 Thiazole And Oxazole Kinase Inhibitors PDXK, MAP3K1, MAP4K2 RIPK1 461/4885DPP4 513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.