Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.50 |
| ▸ | VCP | P55072 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14315416 | 0.90 | EIF4E (0.61) | EIF4ECSNK2A1VCPMAPTMEN1 | |
| SCHEMBL14150266 | 0.87 | EIF4E (0.52) | EIF4ECSNK2A1VCPMAPTMEN1 | |
| SCHEMBL14317624 | 0.87 | EIF4E (0.52) | EIF4ECSNK2A1VCPMAPTMEN1 | |
| SCHEMBL14315465 | 0.84 | ATP4A (0.52) | EIF4ECSNK2A1VCPMAPTMEN1 | |
| SCHEMBL14315418 | 0.84 | EIF4E (0.50) | EIF4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL16404087 | 0.83 | EIF4E (0.49) | EIF4ECSNK2A1VCPMAPTMEN1 | |
| SCHEMBL16404009 | 0.83 | ATP4A (0.54) | EIF4ECSNK2A1MAPTMEN1KMT2A | |
| SCHEMBL14315417 | 0.83 | HSD17B1 (0.49) | EIF4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7532579 | 0.79 | HSD17B1 (0.72) | EIF4ECSNK2A1VCPMAPTMEN1 | |
| SCHEMBL7089339 | 0.78 | GAA (0.51) | EIF4ECSNK2A1VCPMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718290-B1 | COMPOSITIONS AND METHODS FOR MODULATING A KINASE | CLEVEXEL PHARMA (FR) | 2016-05-04 | — | — | EP | disclosed |
| EP-2718290-B1 | COMPOSITIONS AND METHODS FOR MODULATING A KINASE | CLEVEXEL PHARMA (FR) | 2016-05-04 | — | — | EP | disclosed |
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |