Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | EIF4E | P06730 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181984 | 0.88 | EIF4E (0.56) | GAAMGAMSIPKMMGAM2 | |
| SCHEMBL9329912 | 0.81 | ALDH1A1 (0.47) | GAACYP2C9EIF4ERAB9AMEN1 | |
| SCHEMBL7089405 | 0.81 | RAB9A (0.75) | GAAPKMRAB9AMEN1KMT2A | |
| SCHEMBL1786612 | 0.79 | HSD17B1 (0.60) | CYP2C9SCN9AHTR2BACHEALDH1A1 | |
| SCHEMBL7090928 | 0.79 | CYP2C9 (0.56) | GAACYP2C9SCN9ATSHRHTR2B | |
| SCHEMBL14564378 | 0.79 | CYP2C9 (0.62) | GAACYP2C9SCN9AHTR2BACHE | |
| SCHEMBL16404012 | 0.78 | EIF4E (0.55) | GAAMGAMSIPKMMGAM2 | |
| SCHEMBL31351001 | 0.78 | TLR7 (0.62) | CYP2C9SCN9AHTR2BACHEMEN1 | |
| SCHEMBL27993654 | 0.77 | TSHR (0.53) | GAATSHRCSNK2A1VCPCDC7 | |
| Hydrochloric Acid SCHEMBL27746131 | 0.77 | TLR7 (0.60) | CYP2C9SCN9AHTR2BACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144308-A1 | Fructose 1,6-bisphosphatase inhibitors | BAUER PAUL H (US) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144308-A1 | Fructose 1,6-bisphosphatase inhibitors | FBP1, HK1, G6PC1 | GAA 78/4885MGAM 36/4885SI 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.