Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 2/20 | 0.52 |
| ▸ | ATP4B | P51164 | 2/20 | 0.52 |
| ▸ | RHOA | P61586 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SPR | P35270 | 4/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404112 | 0.87 | ATP4A (0.53) | ATP4AATP4BRHOAALDH1A1NPC1 | |
| SCHEMBL16404143 | 0.85 | ATP4A (0.53) | ATP4AATP4BRHOAALDH1A1NPC1 | |
| SCHEMBL16404080 | 0.84 | ATP4A (0.50) | ATP4AATP4BRHOAALDH1A1NPC1 | |
| SCHEMBL14318291 | 0.84 | ATP4A (0.67) | ATP4AATP4BRHOAALDH1A1NPC1 | |
| SCHEMBL16404065 | 0.84 | ATP4A (0.64) | ATP4AATP4BRHOAALDH1A1NPC1 | |
| SCHEMBL14318276 | 0.83 | ATP4A (0.69) | ATP4AATP4BRHOAALDH1A1NPC1 | |
| SCHEMBL14318363 | 0.81 | ATP4A (0.47) | ATP4AATP4BRHOAALDH1A1NPC1 | |
| SCHEMBL16404152 | 0.81 | ATP4A (0.54) | ATP4AATP4BRHOAALDH1A1NPC1 | |
| SCHEMBL14306191 | 0.77 | ATP4A (0.51) | ATP4AATP4BRHOAALDH1A1NPC1 | |
| SCHEMBL14318349 | 0.77 | LMNA (0.51) | ATP4AATP4BALDH1A1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |