Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.64 |
| ▸ | CNR2 | P34972 | 2/20 | 0.64 |
| ▸ | GRM5 | P41594 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CHUK | O15111 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033217 | 0.84 | CNR1 (0.65) | CNR1CNR2GRM5SMN1; SMN2MAPT | |
| SCHEMBL8003176 | 0.80 | SMN1; SMN2 (0.74) | MEN1KMT2ASMN1; SMN2KDM4ENR3C1 | |
| SCHEMBL16404251 | 0.78 | CNR1 (0.61) | CNR1CNR2GRM5 | |
| SCHEMBL4508077 | 0.77 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL16404211 | 0.74 | CNR1 (0.68) | CNR1CNR2GRM5 | |
| SCHEMBL16404261 | 0.73 | CNR1 (0.60) | CNR1CNR2GRM5 | |
| SCHEMBL16404204 | 0.73 | CNR1 (0.67) | CNR1CNR2GRM5KDM4EMAPT | |
| SCHEMBL21294484 | 0.72 | ACSS2 (0.86) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL29433407 | 0.72 | ACSS2 (0.86) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL4683413 | 0.72 | KCNK3 (0.88) | MEN1KMT2AMAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |