Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.60 |
| ▸ | CNR1 | P21554 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | HTR2C | P28335 | 5/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404240 | 0.80 | CNR1 (0.59) | CNR2CNR1RAB9ATP53 | |
| SCHEMBL16404211 | 0.80 | CNR1 (0.68) | CNR2CNR1HTR2AHTR2CSLC6A4 | |
| SCHEMBL2033217 | 0.77 | CNR1 (0.65) | CNR2CNR1RAB9ATP53MAPT | |
| SCHEMBL16404261 | 0.76 | CNR1 (0.60) | CNR2CNR1HTR2AHTR2CSLC6A4 | |
| SCHEMBL16404255 | 0.76 | CNR1 (0.70) | CNR2CNR1HTR2AHTR2CSLC6A4 | |
| SCHEMBL3684239 | 0.76 | CNR1 (0.57) | CNR2CNR1MAPT | |
| SCHEMBL17077648 | 0.75 | CNR2 (0.51) | CNR2CNR1HTR2AHTR2CSLC6A4 | |
| SCHEMBL16404254 | 0.75 | CNR1 (0.56) | CNR2CNR1TP53MAPT | |
| SCHEMBL23889217 | 0.74 | CNR1 (0.56) | CNR2CNR1NPC1 | |
| SCHEMBL4961512 | 0.74 | CNR1 (0.55) | CNR2CNR1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |