Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.59 |
| ▸ | CNR2 | P34972 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404239 | 0.80 | CNR2 (0.60) | CNR1CNR2TP53RAB9A | |
| SCHEMBL16404254 | 0.77 | CNR1 (0.56) | CNR1CNR2KMT2AALDH1A1TP53 | |
| SCHEMBL16404211 | 0.75 | CNR1 (0.68) | CNR1CNR2 | |
| SCHEMBL16404224 | 0.74 | CNR1 (1.00) | CNR1CNR2KMT2AHPGDMEN1 | |
| SCHEMBL22543080 | 0.73 | MAPT (0.68) | KMT2AALDH1A1HPGDALOX15TSHR | |
| SCHEMBL1161997 | 0.73 | NAMPT (0.75) | KMT2AALDH1A1GAAUSP2HTT | |
| SCHEMBL2424556 | 0.72 | RECQL (0.72) | KMT2AALDH1A1HPGDUSP2HTT | |
| SCHEMBL12629886 | 0.72 | POLB (0.64) | KMT2AALDH1A1HPGDTSHRGAA | |
| SCHEMBL13102334 | 0.72 | MMP13 (0.85) | KMT2AALDH1A1HPGDTSHRGAA | |
| SCHEMBL29437161 | 0.72 | MMP13 (0.85) | KMT2AALDH1A1HPGDTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |