Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404240 | 0.77 | CNR1 (0.59) | CNR1CNR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL582322 | 0.75 | SMN1; SMN2 (0.85) | SMN1; SMN2L3MBTL1ALDH1A1APEX1 | |
| SCHEMBL16404239 | 0.75 | CNR2 (0.60) | CNR1CNR2MAPTTP53 | |
| SCHEMBL2936661 | 0.73 | ALDH1A1 (0.78) | SMN1; SMN2KMT2AMEN1ALDH1A1APEX1 | |
| SCHEMBL16404211 | 0.72 | CNR1 (0.68) | CNR1CNR2 | |
| SCHEMBL4961512 | 0.72 | CNR1 (0.55) | CNR1CNR2SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16404224 | 0.72 | CNR1 (1.00) | CNR1CNR2KMT2AMEN1 | |
| SCHEMBL17194791 | 0.71 | SMN1; SMN2 (1.00) | SMN1; SMN2 | |
| SCHEMBL17695175 | 0.70 | ALDH1A1 (0.64) | SMN1; SMN2KMT2AMEN1NOD2L3MBTL1 | |
| SCHEMBL1078509 | 0.70 | TP53 (0.58) | CNR1CNR2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |