SCHEMBL16404388

SCHEMBL16404388

CCCOC1CC1OCC

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12890066 0.80 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2
SCHEMBL10274520 0.78 GBA1 (0.44) ALDH1A1SMN1; SMN2
SCHEMBL12890068 0.77
SCHEMBL91652 0.77 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2
SCHEMBL15062146 0.77 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2
SCHEMBL7878528 0.76
SCHEMBL85121 0.75 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2
SCHEMBL6358144 0.75 GBA1 (0.31) SMN1; SMN2
SCHEMBL16404858 0.72 HSD11B1 (0.32) ALDH1A1SMN1; SMN2
SCHEMBL16844783 0.71 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8936781-B2 Macrocyclic compounds as hepatitis C virus inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2015-01-20 US disclosed