Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91646 | 0.89 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2SSTR4 | |
| SCHEMBL14113760 | 0.89 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2SSTR4 | |
| SCHEMBL91645 | 0.89 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2SSTR4 | |
| SCHEMBL23640807 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2SSTR4 | |
| SCHEMBL21651980 | 0.79 | RET (0.32) | — | |
| SCHEMBL17918946 | 0.79 | GLB1 (0.34) | — | |
| SCHEMBL14900456 | 0.77 | GBA1 (0.46) | ALDH1A1 | |
| SCHEMBL10052432 | 0.77 | GBA1 (0.46) | ALDH1A1 | |
| SCHEMBL15472142 | 0.77 | GBA1 (0.46) | ALDH1A1 | |
| SCHEMBL14890076 | 0.77 | GBA1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129366-B2 | VLA-4 inhibitory drug | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20090233901-A1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233901-A1 | VLA-4 INHIBITORY DRUG | VCAM1, ITGB4, ITGA4 | ALDH1A1 525/4885SMN1; SMN2 4787/4885SSTR4 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.