Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY11 | Q96G91 | 7/20 | 0.76 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.76 |
| ▸ | RECQL | P46063 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.76 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | PKM | P14618 | 4/20 | 0.76 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.76 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.76 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.76 |
| ▸ | USP2 | O75604 | 2/20 | 0.76 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.76 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.76 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.76 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.76 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17903261 | 0.93 | P2RY11 (0.75) | P2RY11HPSERECQLKMT2AHSD17B10 | |
| SCHEMBL16404704 | 0.88 | P2RY11 (0.86) | P2RY11HPSERECQLKMT2AHSD17B10 | |
| Suramin SCHEMBL30312075 | 0.86 | P2RY11 (1.00) | P2RY11HPSERECQLKMT2AHSD17B10 | |
| Suramin SCHEMBL3161 | 0.86 | P2RY11 (1.00) | P2RY11HPSERECQLKMT2AHSD17B10 | |
| Suramin SCHEMBL29357785 | 0.86 | P2RY11 (1.00) | P2RY11HPSERECQLKMT2AHSD17B10 | |
| Suramin SCHEMBL29371906 | 0.86 | P2RY11 (1.00) | P2RY11HPSERECQLKMT2AHSD17B10 | |
| Suramin SCHEMBL30552218 | 0.86 | P2RY11 (1.00) | P2RY11HPSERECQLKMT2AHSD17B10 | |
| SCHEMBL30930073 | 0.84 | P2RY11 (0.85) | P2RY11HPSERECQLKMT2AHSD17B10 | |
| SCHEMBL21686991 | 0.84 | P2RY11 (0.95) | P2RY11HPSERECQLKMT2AHSD17B10 | |
| SCHEMBL11582827 | 0.82 | P2RY11 (0.82) | P2RY11HPSERECQLKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160193294-A1 | COMPOSITIONS COMPRISING E-SELECTIN ANTAGONISTS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2016-07-07 | — | — | US | disclosed |
| EP-2249854-B1 | TREATMENT OF IMMUNOCOMPROMISED CONDITIONS WITH E-SELECTIN ANTAGONIST AND G-CSF | MATER MEDICAL RES INST (AU) | 2015-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160193294-A1 | COMPOSITIONS COMPRISING E-SELECTIN ANTAGONISTS AND USES THEREFOR | SELL, SELP, SELE | P2RY11 831/4885HPSE 271/4885RECQL 2551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.