Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | CTNNB1 | P35222 | 11/20 | 0.61 |
| ▸ | WNT3A | P56704 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404991 | 0.87 | CTNNB1 (0.56) | PKMTSHRALDH1A1CTNNB1WNT3A | |
| SCHEMBL21753281 | 0.84 | PKM (0.65) | PKMTSHRALDH1A1CTNNB1WNT3A | |
| SCHEMBL1443787 | 0.84 | PKM (1.00) | PKMTSHRALDH1A1CTNNB1WNT3A | |
| SCHEMBL653025 | 0.81 | PKM (0.87) | PKMTSHRALDH1A1CTNNB1WNT3A | |
| Gamma-Aminobutyric Acid SCHEMBL9959686 | 0.81 | PKM (0.81) | PKMTSHRALDH1A1CTNNB1WNT3A | |
| SCHEMBL4259988 | 0.78 | ALDH1A1 (1.00) | PKMTSHRALDH1A1CTNNB1WNT3A | |
| Dalosirvat SCHEMBL653870 | 0.77 | CTNNB1 (1.00) | PKMTSHRALDH1A1CTNNB1WNT3A | |
| SCHEMBL21753357 | 0.76 | CTNNB1 (0.63) | PKMTSHRALDH1A1CTNNB1WNT3A | |
| SCHEMBL22638726 | 0.75 | CTNNB1 (0.72) | PKMTSHRALDH1A1CTNNB1WNT3A | |
| SCHEMBL21770322 | 0.75 | HPGD (0.55) | PKMTSHRALDH1A1CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2656072-B1 | MULTI-ANALYTE MICROARRAYS USING TAG-SPECIFIC ANTIBODIES AND TAG-ANCHORED ANTIBODIES | RANDOX LAB LTD (GB) | 2015-01-21 | — | — | EP | disclosed |