Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073283 | 0.90 | GABRA1 (0.42) | RAPGEF4GABRA1GABRB1LMNASCN4A | |
| SCHEMBL11985992 | 0.84 | ALDH1A1 (0.47) | RAPGEF4GABRA1GABRB1ALDH1A1LMNA | |
| SCHEMBL18886070 | 0.81 | GABRA1 (0.52) | RAPGEF4GABRA1GABRB1LMNASCN4A | |
| SCHEMBL12237882 | 0.80 | LMNA (0.39) | RAPGEF4ALDH1A1LMNATSHRHTT | |
| SCHEMBL19121891 | 0.79 | GABRA1 (0.35) | RAPGEF4GABRA1GABRB1LMNASCN4A | |
| SCHEMBL19304128 | 0.79 | GABRA1 (0.45) | GABRA1GABRB1ALDH1A1LMNASCN4A | |
| SCHEMBL24663933 | 0.76 | CYP3A4 (0.52) | GABRA1GABRB1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL19869248 | 0.76 | MAP3K14 (0.41) | GABRA1GABRB1ALDH1A1SCN4ATSHR | |
| SCHEMBL19126691 | 0.75 | GABRA1 (0.39) | RAPGEF4GABRA1GABRB1ALDH1A1LMNA | |
| SCHEMBL13220712 | 0.75 | GABRA1 (0.56) | GABRA1GABRB1ALDH1A1LMNAAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795953-B2 | Organometallic catalysts | BERGEN TEKNOLOGIOVERFORING AS (NO) | 2017-10-24 | — | — | US | disclosed |
| US-20160214098-A1 | NOVEL ORGANOMETALLIC CATALYSTS | BERGEN TEKNOLOGIOVERFORING AS (NO) | 2016-07-28 | — | — | US | disclosed |
| US-9303100-B2 | Organometallic catalysts | BERGEN TEKNOLOGIOVERFORING AS (NO) | 2016-04-05 | — | — | US | disclosed |
| US-20150025212-A1 | NOVEL ORGANOMETALLIC CATALYSTS | BERGEN TEKNOLOGIOVERFORING AS (NO) | 2015-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214098-A1 | NOVEL ORGANOMETALLIC CATALYSTS | ZKSCAN2, ZC3HAV1L, ZRANB2 | RAPGEF4 1279/4885GABRA1 2667/4885GABRB1 3166/4885 |
| US-20150025212-A1 | NOVEL ORGANOMETALLIC CATALYSTS | ZKSCAN2, ZC3HAV1L, ZRANB2 | RAPGEF4 1279/4885GABRA1 2667/4885GABRB1 3166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.