Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830503 | 0.93 | HPGD (0.65) | HPGDDUSP3GAALMNAKDM4E | |
| SCHEMBL1606290 | 0.89 | CA12 (0.66) | HPGDDUSP3GAALMNAKDM4E | |
| SCHEMBL4512998 | 0.83 | HPGD (0.50) | HPGDDUSP3GAAKDM4ECA12 | |
| SCHEMBL3229195 | 0.83 | HPGD (0.81) | HPGDDUSP3GAALMNAKDM4E | |
| SCHEMBL5429820 | 0.83 | HPGD (0.60) | HPGDDUSP3GAALMNAKDM4E | |
| SCHEMBL16450869 | 0.82 | HPGD (0.74) | HPGDDUSP3GAALMNAKDM4E | |
| SCHEMBL6206098 | 0.82 | GAA (0.66) | HPGDDUSP3GAALMNAKDM4E | |
| SCHEMBL3903156 | 0.82 | GAA (0.76) | HPGDDUSP3GAALMNAKDM4E | |
| SCHEMBL29526410 | 0.81 | CA12 (0.50) | HPGDDUSP3GAAKDM4ECA12 | |
| SCHEMBL14468582 | 0.79 | HPGD (0.70) | HPGDDUSP3GAALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510413-A | DCLK1 kinase inhibitor and preparation method and application thereof | 杭州医学院 | 2024-02-06 | — | — | CN | claimed |
| CN-107189197-B | Comprehensive conveying pipe for high-strength insulating flame-retardant pipeline gallery | 上海中塑管业有限公司 | 2020-05-12 | — | — | CN | claimed |
| CN-105385011-B | A kind of TPV compositions and automobile collision preventing billot | 嘉兴市博尔塑胶有限公司 | 2018-07-31 | — | — | CN | claimed |
| CN-106220994-B | A kind of high intensity PP-RCT anti-flaming tubular products and preparation method | 刘志光 | 2018-06-01 | — | — | CN | claimed |
| EP-2040711-A2 | 2-OXO-1,2-DIHYDROQUINOLINE DERIVATIVES, COMPOSITIONS, AND USES THEREOF AS ANTIPROLIFERATIVE AGENTS | Amphora Discovery Corporation (US) | 2009-04-01 | — | — | EP | claimed |
| WO-2007136592-A2 | 2-0X0-L,2-DIHYDR0QUIN0LINE DERIVATIVES, COMPOSITIONS, AND USES THEREOF AS ANTIPROLIFERATIVE AGENTS | AMPHORA DISCOVERY CORPORATION (US) | 2007-11-29 | — | — | WO | claimed |
| CN-114450283-B | 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2024-05-07 | — | — | CN | disclosed |
| CN-117510413-A | DCLK1 kinase inhibitor and preparation method and application thereof | 杭州医学院 | 2024-02-06 | — | — | CN | disclosed |
| EP-4003988-A1 | 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | Les Laboratoires Servier (FR) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450283-A | 3, 6-diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2022-05-06 | — | — | CN | disclosed |
| CN-107189197-B | Comprehensive conveying pipe for high-strength insulating flame-retardant pipeline gallery | 上海中塑管业有限公司 | 2020-05-12 | — | — | CN | disclosed |
| CN-105385011-B | A kind of TPV compositions and automobile collision preventing billot | 嘉兴市博尔塑胶有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-106220994-B | A kind of high intensity PP-RCT anti-flaming tubular products and preparation method | 刘志光 | 2018-06-01 | — | — | CN | disclosed |
| US-20020188015-A1 | Method and composition for rejuvinating cells, tissues organs, hair and nails | FARRINGTON PHARMACEUTICALS, LLC | 2002-12-12 | — | — | US | disclosed |
| WO-2002083863-A2 | THIAZOLE AND OTHER HETEROCYCLIC LIGANDS AND USE THEREOF | SEPRACOR, INC. (US) | 2002-10-24 | — | — | WO | disclosed |
| WO-2002062301-A2 | METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS | FARRINGTON PHARMACEUTICALS, LLC (US) | 2002-08-15 | — | — | WO | disclosed |
| EP-0790997-A2 | 6-ARYL PYRIDO( 2,3-d]PYRIMIDINES AND NAPHTHYRIDINES FOR INHIBITING PROTEIN TYROSINE KINASE MEDIATED CELLULAR PROLIFERATION | WARNER-LAMBERT COMPANY (US) | 1997-08-27 | — | — | EP | disclosed |
| EP-0230334-B1 | A INDENOTHIAZOLE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-4877876-A | ANTIULCER AGENTS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0230334-A1 | A indenothiazole derivative and process for preparing the same | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1987-07-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020188015-A1 | Method and composition for rejuvinating cells, tissues organs, hair and nails | TERT, TELO2, HKDC1 | HPGD 3684/4885DUSP3 1624/4885GAA 3996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.