SCHEMBL3903156

SCHEMBL3903156

NC(=O)NCCCN1CCOCC1

nearest known ligand 0.76

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.76
LMNA P02545 2/20 0.69
KDM4E B2RXH2 2/20 0.69
HPGD P15428 1/20 0.64
DUSP3 P51452 1/20 0.64
ALDH1A1 P00352 4/20 0.60
MAPK1 P28482 1/20 0.60
HIF1A Q16665 1/20 0.60
RAB9A P51151 1/20 0.59
EPHX1 P07099 1/20 0.56
TSHR P16473 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
EPHX2 P34913 1/20 0.54
POLB P06746 1/20 0.54
PAOX Q6QHF9 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1462089 0.95 GAA (0.69) GAALMNAKDM4EHPGDDUSP3
SCHEMBL1461242 0.89 GAA (0.60) GAALMNAKDM4EALDH1A1TSHR
SCHEMBL29497614 0.86 GAA (1.00) GAALMNAKDM4EHPGDDUSP3
SCHEMBL13655375 0.85 LMNA (0.84) GAALMNAKDM4EHPGDDUSP3
SCHEMBL2347336 0.85 GAA (0.70) GAALMNAKDM4EHPGDDUSP3
SCHEMBL12434010 0.85 GAA (0.69) GAALMNAKDM4EHPGDDUSP3
SCHEMBL76649 0.84 GAA (0.68) GAALMNAKDM4EHPGDDUSP3
SCHEMBL8594860 0.83 GAA (0.53) GAALMNAKDM4EMAPK1SMN1; SMN2
SCHEMBL12330918 0.83 GAA (0.67) GAALMNAKDM4EHPGDDUSP3
SCHEMBL8762651 0.82 GAA (0.66) GAALMNAKDM4EHPGDDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510413-A DCLK1 kinase inhibitor and preparation method and application thereof 杭州医学院 2024-02-06 CN claimed
US-9657129-B2 Cyclic amine compound and process for producing polyurethane resin by using it TOSOH CORPORATION (JP) 2017-05-23 US claimed
CN-103270039-B Cyclic amine compound and method for producing polyurethane resin using same TOSOH CORP. (JP) 2016-03-30 CN claimed
EP-2657237-B1 CYCLIC AMINE COMPOUND, AND PROCESS FOR PRODUCING POLYURETHANE RESIN USING SAME TOSOH CORP (JP) 2015-05-20 EP claimed
US-20130289232-A1 NOVEL CYCLIC AMINE COMPOUND AND PROCESS FOR PRODUCING POLYURETHANE RESIN BY USING IT TOSOH CORPORATION (JP) 2013-10-31 US claimed
EP-2657237-A1 NOVEL CYCLIC AMINE COMPOUND, AND PROCESS FOR PRODUCING POLYURETHANE RESIN USING SAME Tosoh Corporation (JP) 2013-10-30 EP claimed
EP-1443065-B1 Low acid organometallic catalyst for the production of flexible, semi-flexible and rigid polyurethane foams AIR PROD & CHEM (US) 2006-09-13 EP claimed
EP-1534766-A1 PROCESS FOR PREPARING POLYURETHANE FOAM GENERAL ELECTRIC COMPANY (US) 2005-06-01 EP claimed
US-6825238-B2 BISMUTH CARBOXYLATE OR BISMUTH SULFONATE HAVING LESS THAN 34% FREE ACID AS THE ORGANOMETALLIC CATALYST AIR PRODUCTS AND CHEMICALS, INC. 2004-11-30 US claimed
US-6818675-B2 USING REACTION PRODUCT OF TERTIARY AMINE AND ACID AS POLYMERIZATION CATALYST GENERAL ELECTRIC COMPANY 2004-11-16 US claimed
EP-0877042-B1 Reactive catalyst compositions for improving water blown polyurethane foam performance AIR PROD & CHEM (US) 2004-09-22 EP claimed
EP-1443065-A1 Low acid organometallic catalyst for the production of flexible, semi-flexible and rigid polyurethane foams AIR PRODUCTS AND CHEMICALS, INC. (US) 2004-08-04 EP claimed
US-20040147626-A1 LOW ACID ORGANOMETALLIC CATALYST FOR THE PRODUCTION OF FLEXIBLE, SEMI-FLEXIBLE AND RIGID POLYURETHANE FOAMS EVONIK DEGUSSA GMBH (DE) 2004-07-29 US claimed
EP-1390369-A1 4-AMINO-5-PHENYL-7-CYCLOBUTYL-PYRROLO(2,3-D)PYRIMIDINE DERIVATIVES Novartis AG (CH) 2004-02-25 EP claimed
WO-2004013201-A1 PROCESS FOR PREPARING POLYURETHANE FOAM GENERAL ELECTRIC COMPANY (US) 2004-02-12 WO claimed
US-20040029986-A1 Process for preparing polyurethane foam CROMPTON CORPORATION 2004-02-12 US claimed
WO-2002092599-A1 4-AMINO-5-PHENYL-7-CYCLOBUTYL-PYRROLO (2,3-D) PYRIMIDINE DERIVATIVES NOVARTIS AG (CH) 2002-11-21 WO claimed
EP-0877042-A1 Reactive catalyst compositions for improving water blown polyurethane foam performance AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-11-11 EP claimed
CN-119841829-A Compounds for the treatment of PI3K gamma mediated diseases and uses thereof 中国科学院合肥物质科学研究院 2025-04-18 CN disclosed
EP-0877042-A1 Reactive catalyst compositions for improving water blown polyurethane foam performance AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-11-11 EP disclosed