Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616930 | 0.87 | ESR1 (0.56) | IDH1MEN1CYP3A4HPGDALOX15 | |
| SCHEMBL2883692 | 0.87 | ESR1 (0.56) | IDH1MEN1CYP3A4HPGDALOX15 | |
| SCHEMBL21360622 | 0.82 | ESR1 (0.54) | IDH1MEN1CYP3A4HPGDALOX15 | |
| SCHEMBL16406435 | 0.79 | PDK2 (0.41) | CYP3A4HPGDPDK2BCL2L1ESR1 | |
| SCHEMBL10886054 | 0.78 | IDH1 (0.70) | IDH1MEN1CYP3A4HPGDALOX15 | |
| SCHEMBL9173452 | 0.78 | IDH1 (0.70) | IDH1MEN1CYP3A4HPGDALOX15 | |
| SCHEMBL17192496 | 0.77 | ESR1 (0.52) | MEN1CYP3A4HPGDALOX15KMT2A | |
| SCHEMBL11934320 | 0.76 | ESR1 (0.50) | MEN1CYP3A4HPGDALOX15KMT2A | |
| SCHEMBL13534657 | 0.76 | ESR1 (0.53) | MEN1CYP3A4HPGDALOX15KMT2A | |
| SCHEMBL900437 | 0.75 | TRPA1 (0.44) | ALOX15HSD17B10PDK2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206287-B2 | Fluorene derivatives and lens using the same | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2015-12-08 | — | — | US | disclosed |
| US-9206287-B2 | Fluorene derivatives and lens using the same | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2015-12-08 | — | — | US | disclosed |
| US-20150025215-A1 | Fluorene derivatives and lens using the same | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2015-01-22 | — | — | US | disclosed |
| US-20150025215-A1 | Fluorene derivatives and lens using the same | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2015-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025215-A1 | Fluorene derivatives and lens using the same | UACA, AFF1, AFF2 | IDH1 4199/4885MEN1 506/4885CYP3A4 2904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.