Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820524 | 0.89 | SLC6A9 (0.41) | PDK2HPGDSMN1; SMN2SLC6A9DRD2 | |
| SCHEMBL16406432 | 0.84 | SLC6A9 (0.40) | PDK2HPGDSMN1; SMN2SLC6A9DRD2 | |
| SCHEMBL16406434 | 0.82 | ESR1 (0.41) | PDK2ESR1 | |
| SCHEMBL16406429 | 0.79 | IDH1 (0.49) | PDK2HPGDESR1CYP3A4BCL2L1 | |
| SCHEMBL16406431 | 0.78 | ESR1 (0.42) | PDK2ESR1CYP1A2 | |
| SCHEMBL16021966 | 0.75 | HPGD (0.43) | HPGDSMN1; SMN2SLC6A9DRD2DRD1 | |
| SCHEMBL7907565 | 0.75 | HRH1 (0.42) | HPGDSMN1; SMN2SLC6A9DRD2DRD1 | |
| SCHEMBL22187689 | 0.74 | SLC6A9 (0.46) | PDK2SLC6A9TP53LMNA | |
| SCHEMBL29609175 | 0.74 | SLC6A9 (0.46) | PDK2SLC6A9TP53LMNA | |
| SCHEMBL383592 | 0.74 | ESR1 (0.43) | PDK2SMN1; SMN2ESR1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206287-B2 | Fluorene derivatives and lens using the same | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2015-12-08 | — | — | US | disclosed |
| US-9206287-B2 | Fluorene derivatives and lens using the same | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2015-12-08 | — | — | US | disclosed |
| US-20150025215-A1 | Fluorene derivatives and lens using the same | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2015-01-22 | — | — | US | disclosed |
| US-20150025215-A1 | Fluorene derivatives and lens using the same | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2015-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025215-A1 | Fluorene derivatives and lens using the same | UACA, AFF1, AFF2 | PDK2 3663/4885HPGD 3652/4885SMN1; SMN2 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.