SCHEMBL16409578

SCHEMBL16409578

c1ccc2c(c1)oc1ccc(-n3c4ccccc4c4ccc(-n5c6ccccc6c6ccccc65)cc43)cc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.46
▸ KDM4E B2RXH2 4/20 0.46
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ ALDH1A1 P00352 3/20 0.46
▸ HPGD P15428 3/20 0.46
▸ SMN1; SMN2 Q16637 3/20 0.46
▸ NPC1 O15118 2/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ ATM Q13315 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ AHR P35869 2/20 0.42
▸ CYP1A2 P05177 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ CHRNA7 P36544 1/20 0.37
▸ KCNH2 Q12809 1/20 0.37
▸ LMNA P02545 1/20 0.36
▸ MAOA P21397 4/20 0.36
▸ GLA P06280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16409634 1.00 MAPT (0.46) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL25757233 0.97 KDM4E (0.47) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL10144980 0.95 MAPT (0.50) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL1636722 0.94 MAPT (0.46) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL26049310 0.94 KDM4E (0.44) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL24307491 0.93 MAPT (0.49) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL18381828 0.93 MAPT (0.49) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL12158863 0.92 MAPT (0.42) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL1635406 0.92 KDM4E (0.47) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL1637492 0.92 MAPT (0.45) MAPTKDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024135278-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT 日鉄ケミカル&マテリアル株式会社 2024-06-27 — — WO disclosed
US-20230363272-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 — — US disclosed
US-20230363272-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 — — US disclosed
US-20230276644-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-08-31 — — US disclosed
US-20230276644-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-08-31 — — US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 — — US disclosed
EP-2966706-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-01-13 — — EP disclosed
WO-2015009102-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 (KR) 2015-01-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 MAPT 1163/4885KDM4E 3396/4885MEN1 1828/4885
US-20230363272-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME LAGE3, CRY1, CRY2 MAPT 2702/4885KDM4E 1777/4885MEN1 746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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