Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410611 | 0.80 | — | — | |
| SCHEMBL16410774 | 0.78 | MEN1 (0.36) | P2RX7CHRM2MAPT | |
| SCHEMBL16410776 | 0.75 | NOS3 (0.35) | P2RX7CHRM2MAPT | |
| SCHEMBL16410780 | 0.75 | MEN1 (0.35) | P2RX7CHRM2MAPT | |
| SCHEMBL16410701 | 0.74 | PIK3CA (0.33) | P2RX7 | |
| SCHEMBL16410731 | 0.74 | KDM4E (0.30) | — | |
| SCHEMBL16410683 | 0.74 | PIK3CA (0.32) | P2RX7 | |
| SCHEMBL16410845 | 0.74 | DHFR (0.31) | MAPT | |
| SCHEMBL16410718 | 0.73 | PIK3CA (0.34) | P2RX7CHRM2 | |
| SCHEMBL16410835 | 0.73 | NOS1 (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007730-A1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2015-01-22 | — | — | WO | disclosed |