Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT2 | Q9BWD1 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410847 | 0.89 | ACAT2 (0.37) | ACAT2 | |
| SCHEMBL16410784 | 0.88 | ACAT2 (0.43) | ACAT2 | |
| SCHEMBL16410694 | 0.84 | ACAT2 (0.47) | ACAT2CRHBPCRHR2 | |
| SCHEMBL16410736 | 0.81 | ACAT2 (0.44) | ACAT2 | |
| SCHEMBL17758089 | 0.77 | LMNA (0.36) | ACAT2 | |
| SCHEMBL16410766 | 0.76 | ACAT2 (0.47) | ACAT2 | |
| SCHEMBL16410755 | 0.75 | ACAT2 (0.43) | ACAT2CRHBPCRHR2 | |
| SCHEMBL16410803 | 0.74 | ACAT2 (0.37) | ACAT2 | |
| SCHEMBL16410816 | 0.74 | ACAT2 (0.45) | ACAT2 | |
| SCHEMBL17757825 | 0.73 | ACAT2 (0.38) | ACAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007730-A1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2015-01-22 | — | — | WO | disclosed |