Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410618 | 0.85 | KDM4E (0.31) | KMT2A | |
| SCHEMBL16410739 | 0.82 | KMT2A (0.39) | KMT2A | |
| SCHEMBL16410606 | 0.82 | ACAT2 (0.40) | KMT2A | |
| SCHEMBL16410622 | 0.81 | KMT2A (0.37) | KMT2A | |
| SCHEMBL16410832 | 0.80 | KDM4E (0.35) | MEN1KMT2A | |
| SCHEMBL17757421 | 0.79 | FFAR1 (0.39) | MEN1KMT2A | |
| SCHEMBL16410790 | 0.78 | LMNA (0.36) | MEN1KMT2A | |
| SCHEMBL16410749 | 0.78 | TSHR (0.33) | MEN1KMT2A | |
| SCHEMBL17757418 | 0.77 | MEN1 (0.49) | MEN1KMT2A | |
| SCHEMBL31307839 | 0.77 | MEN1 (0.49) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007730-A1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2015-01-22 | — | — | WO | disclosed |