Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410858 | 0.91 | PIK3CA (0.35) | PIK3CB | |
| SCHEMBL17758076 | 0.89 | PIK3CB (0.36) | PIK3CB | |
| SCHEMBL16410792 | 0.89 | KMT2A (0.38) | — | |
| SCHEMBL16410700 | 0.88 | ACAT2 (0.38) | — | |
| SCHEMBL16410806 | 0.84 | PIK3CB (0.30) | PIK3CB | |
| SCHEMBL16410629 | 0.82 | PIK3CA (0.36) | PIK3CB | |
| SCHEMBL17757055 | 0.80 | PIK3CA (0.40) | PIK3CB | |
| SCHEMBL17758090 | 0.78 | KCNN3 (0.36) | PIK3CB | |
| SCHEMBL16410758 | 0.78 | KMT2A (0.36) | — | |
| SCHEMBL16410624 | 0.78 | SMN1; SMN2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007730-A1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2015-01-22 | — | — | WO | disclosed |